Weekend NFL Betting Preview

The Arizona Cardinals have lost four games in a row as they head into their matchup on Sunday afternoon on the road against the Green Bay Packers as the biggest underdog on the NFL betting board. As well, with the Cardinals at 1-7 on the OVER/UNDER the contest will attract the attention of totals bettors at the sportsbooks.

Arizona lost 24-3 at home to the San Francisco 49ers on Monday Night Football, and their struggling offense has managed to put up just 36 points over their past four games. And with starting QB Kevin Kolb still out with rib and shoulder injuries, the Cardinals (4-4 SU, 3-4-1 ATS) are pegged as 12-point road underdogs on the NFL betting lines at 5Dimes for their game against the Packers.

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Green Bay (5-3 SU, 3-5 ATS) has won three games in a row, including a 24-15 win over Jacksonville last time out. The Packers sit at 5-3 on the OVER/UNDER for the year, while four of the past five Green Bay/Arizona games have been UNDER results.

The other big underdogs on the NFL betting lines at 5Dimes for this week are the Buffalo Bills at +11.5 on the road against the Houston Texans on Sunday afternoon, and the Kansas City Chiefs at +9 on the road against the San Diego Chargers on Thursday night. The Chiefs have the worst ATS record in the league at 2-5 (1-6 SU) this season, and they're 2-3 SU but 3-2 ATS over their past five against the Chargers.

There are plenty of home underdogs on the 5Dimes NFL odds for this week, including Cleveland +3.5 vs. Baltimore, Tennessee +3.5 vs. Chicago, Jacksonville +3.5 vs. Detroit, Indianapolis +1.5 vs. Miami, and Cincinnati +3.5 vs. Denver. The Broncos, who are coming off an easy win over the Saints on Sunday Night Football, have been tagged with an ATS loss in five of their past seven games against the Bengals.

Rounding out the NFL betting slate for the week are Carolina at Washington (-3.5), Tampa Bay at Oakland (pick), Minnesota at Seattle (-5), Pittsburgh at the Giants (-3), Philadelphia at New Orleans (-3), and Dallas at Atlanta (-4). The Falcons are 7-0 SU and 5-2 ATS on the season, with the Cowboys at 3-4 both SU and ATS. The OVER has paid out for NFL totals bettors in the last three meetings between those two teams.