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Indianapolis Colts vs. San Francisco 49ers

The Indianapolis Colts and the San Francisco 49ers will both be trying to pick up a win on Sunday when they battle at Levi's Stadium.

Oddsmakers opened the 49ers as -3.5-point favorites versus the Colts, while the game's total opened at 44.5.

In their last action, San Francisco was a 17-10 loser on the road against the Cardinals. They failed to cover the +6-point spread as underdogs, while the combined score (27) was profitable news for UNDER bettors.

The Colts were a 31-3 winner in their most recent outing at home against the Texans. They covered the -11.5-point spread as favorites, while the total score (34) made winners of UNDER bettors.

Indianapolis:
Team record: 2-4 SU,4-2 ATS
Indianapolis is 4-1 ATS in its last 5 games
Indianapolis is 2-5 SU in its last 7 games
Indianapolis is 7-2 ATS in its last 9 games on the road

San Francisco:
Team record: 2-3 SU,1-4 ATS
Current Streak: lost 3 straight games.
San Francisco is 1-4 ATS in its last 5 games
San Francisco is 4-10 SU in its last 14 games
San Francisco is 1-5 ATS in its last 6 games at home

Next up:
Indianapolis home to Tennessee Sunday, October 31
San Francisco at Chicago Sunday, October 31