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Jacksonville Jaguars vs. Indianapolis Colts

If familiarity breeds contempt, there should be animosity aplenty on Sunday when the Jacksonville Jaguars and the Indianapolis Colts meet at Lucas Oil Stadium.

Oddsmakers opened the Colts as -10.5-point favorites versus the Jaguars, while the game's total opened at 48.

The Colts were a 45-30 winner in their most recent outing at home against the Jets. They covered the -10-point spread as favorites, while the total score (75) made winners of OVER bettors.

Last time out for Jacksonville, they were a 9-6 winner as they battled the Bills at home. The Jaguars covered in the match as a +14.5-point underdog, while 15 combined points moved the game UNDER for totals bettors.

Jacksonville:
Team record: 2-6 SU,3-5 ATS
Jacksonville is 0-5 SU in its last 5 games on the road
Jacksonville is 10-1-1 ATS in its last 12 games when playing Indianapolis
The total has gone OVER in 4 of Jacksonville's last 6 games when playing Indianapolis

Indianapolis:
Team record: 4-5 SU,6-3 ATS
Indianapolis is 17-8 SU in its last 25 games at home
Indianapolis is 1-10-1 ATS in its last 12 games when playing Jacksonville
The total has gone OVER in 4 of Indianapolis's last 6 games when playing Jacksonville

Next up:
Jacksonville home to San Francisco Sunday, November 21
Indianapolis at Buffalo Sunday, November 21