Massachusetts Minutemen Game Logs
| event date | Opponent | Type | Result | score | ATS | Line | OU | Total | preview available | recap available |
|---|---|---|---|---|---|---|---|---|---|---|
| Sep 4, 2021 | @ Pittsburgh | REG | L | 51-7 | L | 37.5 | O | 56 | Preview | Recap |
| Sep 11, 2021 | vs Boston College | REG | L | 45-28 | W | 39 | O | 57 | Preview | Recap |
| Sep 18, 2021 | vs Eastern Michigan | REG | L | 42-28 | W | 22 | O | 56.5 | Preview | Recap |
| Sep 25, 2021 | @ Coastal Carolina | REG | L | 53-3 | L | 36 | U | 66 | Preview | Recap |
| Oct 2, 2021 | vs Toledo | REG | L | 45-7 | L | 27 | U | 56.5 | Preview | Recap |
| Oct 9, 2021 | vs Connecticut | REG | W | 27-13 | W | 3 | U | 57 | Preview | Recap |
| Oct 23, 2021 | @ Florida State | REG | L | 59-3 | L | 35 | O | 59 | Preview | Recap |
| Oct 30, 2021 | @ Liberty | REG | L | 62-17 | L | 35.5 | O | 56 | Preview | Recap |
| Nov 6, 2021 | vs Rhode Island | REG | L | 35-22 | L | -2.5 | O | 55.5 | Preview | Recap |
| Nov 13, 2021 | vs Maine | REG | L | 35-10 | L | 5 | U | 58.5 | Preview | Recap |
| Nov 20, 2021 | @ Army | REG | L | 33-17 | W | 37 | U | 56 | Preview | No |
| Nov 27, 2021 | @ New Mexico State | REG | L | 44-27 | L | 7 | O | 59 | No | Recap |