Louisville Cardinals Game Logs
| event date | Opponent | Type | Result | score | ATS | Line | OU | Total | preview available | recap available |
|---|---|---|---|---|---|---|---|---|---|---|
| Aug 30, 2025 | vs Eastern Kentucky | REG | W | 51-17 | L | -38.5 | O | 56.5 | Preview | No |
| Sep 5, 2025 | vs James Madison | REG | W | 28-14 | L | -14.5 | U | 56.5 | Preview | Recap |
| Sep 20, 2025 | vs Bowling Green | REG | W | 40-17 | L | -26.5 | O | 51 | Preview | Recap |
| Sep 27, 2025 | @ Pittsburgh | REG | W | 34-27 | W | -3 | O | 54.5 | Preview | Recap |
| Oct 4, 2025 | vs Virginia | REG | L | 30-27 | L | -6.5 | U | 60 | Preview | Recap |
| Oct 17, 2025 | @ Miami-FL | REG | W | 24-21 | W | 10.5 | U | 49.5 | Preview | Recap |
| Oct 25, 2025 | vs Boston College | REG | W | 38-24 | L | -25.5 | O | 54.5 | Preview | Recap |
| Nov 1, 2025 | @ Virginia Tech | REG | W | 28-16 | W | -10.5 | U | 52.5 | Preview | Recap |
| Nov 8, 2025 | vs California | REG | L | 29-26 | L | -18.5 | O | 49.5 | Preview | Recap |
| Nov 14, 2025 | vs Clemson | REG | 0-0 | Preview | No | |||||
| Nov 22, 2025 | @ Southern Methodist | REG | 0-0 | No | No | |||||
| Nov 29, 2025 | vs Kentucky | REG | 0-0 | No | No |